LAMOTRIGINE LEVEL, SERUM

test app

TEST NAME: LAMOTRIGINE, SERUM

LAB DEPT: Core Lab Sendouts

SPECIMEN REQUIREMENTS

Specimen Type:	Blood
Container/Tube
Preferred:	Gold/Red SST Vacutainer®.
Acceptable:	Plain, red-top Vacutainer®.
Collection Volume:	2.0 mL (minimum 1.0 mL)
Patient Preparation:	None
Sample Rejection:	Mislabeled or unlabeled specimens.
Special Instructions:	Collect specimen immediately before next scheduled dose. For sustained-release formulations ONLY, collect a minimum of 12 hours after last dose. Send to lab promptly.

LOGISTICS

Test Availability:	Daily
Turnaround Time:	2-4 days
Test set-up:	Monday-Sunday
Lab Testing Section:	Send-outs
Referred to:	Mayo Medical Laboratories (MMLI) / Test ID: LAMO

INTERPRETIVE

Reference Range:	Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL
Critical Values:	None established
Limitations:	NA
Methodology:	Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Test Classification:	This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

ADDITIONAL INFORMATION

For SLCH Laboratory use only

Lab Processing instructions:	Centrifuge specimen to separate within 2 hours of collection. Aliquot sample into a 5-mL screw-capped, plastic vial for transport.
Processed Volume:	1.0 mL (minimum 0.5 mL) serum
Transport Temperature:	Refrigerated
Analyte Stability:	PROCESSED: Ambient: 28 days Refrigerated: 28 days Frozen: 28 days
Notes:	Serum separator tube acceptable but serum should be removed from gel within 24 hours of collection.

GENERAL INFORMATION

EPIC order name:	Lamotrigine Level (EPIC Test# LAB475)
Cerner order name:	Lamotrigine
CPT Codes:	80175
LOINC Value:	6948-4
Synonyms:	Lamictal
Last Updated: 11/22
Last Reviewed: 11/22