LEVETIRACETAM (KEPPRA) LEVEL, SERUM
test app
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Specimen Type:
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Blood |
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Container/Tube
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Preferred:
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Gold/Red SST Vacutainer®.
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Acceptable:
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Plain, red-top Vacutainer®.
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Collection Volume:
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2.0 mL (minimum 1.0 mL)
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Patient Preparation:
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None
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Sample Rejection:
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Mislabeled or unlabeled specimens.
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Special Instructions:
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Collect specimen immediately before next scheduled dose.
For sustained-release formulations ONLY, collect specimen a minimum of 12 hours after last dose.
Send to lab promptly.
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Test Availability:
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Daily
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Turnaround Time:
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2-4 days
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Test set-up:
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Monday-Sunday
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Lab Testing Section:
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Send-outs
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Referred to:
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Mayo Medical Laboratories (MMLI) / Test ID: LEVE
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Therapeutic Range:
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10.0-40.0 mcg/mL
Therapeutic ranges are based on specimen collected at trough (ie, immediately before the next dose)
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Critical Values:
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Toxic levels have not been well established
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Limitations:
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NA
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Methodology:
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Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
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Test Classification:
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This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
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Lab Processing instructions:
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Centrifuge specimen to separate within 2 hours of collection. Aliquot serum into a 5-mL screw-capped plastic vial for transport.
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Processed Volume:
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1.0 mL (minimum 0.5 mL) serum
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Transport Temperature:
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Refrigerated
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Analyte Stability:
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PROCESSED:
Ambient: 28 days
Refrigerated: 28 days
Frozen: 28 days
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Notes:
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None
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EPIC order name:
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Levetiracetam Level (EPIC Test# LAB477)
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Cerner order name:
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Levetiracetam
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CPT Codes:
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80177
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LOINC Value:
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30471-7
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Synonyms:
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Keppra
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Last Updated: 12/20
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Last Reviewed: 12/23
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