INSULIN-LIKE GROWTH FACTOR 1 (IGF1), BLOOD
test app
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Specimen Type:
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Blood |
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Container/Tube
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Preferred:
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Mint green-top (lithium heparin)
Vacutainer®.
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Acceptable:
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Gold/Red SST Vacutainer® or Plain,
red-top Vacutainer®.
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Collection Volume:
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2.0 mL (minimum 0.6 mL)
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Patient Preparation:
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Sample should not be taken from patients receiving therapy with high
biotin doses (i.e. >5 mg/day) until at least 8 hours following the last
biotin administration.
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Sample Rejection:
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Specimens that are grossly hemolyzed.
Mislabeled or unlabeled specimens.
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Special Instructions:
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None
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Test Availability:
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Daily
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Test set-up:
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Monday-Sunday
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Cut-off time:
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None; performed as received
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Turnaround Time:
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same day, results available 2 hours from receipt in
lab
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Lab Testing Section:
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Chemistry
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Reference Range:
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Age: years
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Male
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Female
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<2
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10-200
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10-200
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2-3
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10-250
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10-250
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3-4
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20-250
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20-250
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4-5
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30-250
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30-250
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5-6
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40-250
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40-250
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6-7
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50-275
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45-250
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7-8
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50-300
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45-300
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8-9
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60-350
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50-350
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9-10
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70-400
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60-400
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10-11
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70-450
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70-500
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11-12
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80-500
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90-600
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12-13
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85-550
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100-650
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13-14
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90-600
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110-700
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14-15
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95-620
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115-750
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15-16
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100-650
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120-700
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16-17
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100-650
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120-600
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17-18
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100-600
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120-500
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18-20
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90-500
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100-400
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20-22
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80-400
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80-350
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23-25
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65-350
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70-320
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26-30
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60-330
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65-300
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31-35
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55-300
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60-280
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36-40
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50-300
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55-250
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41-45
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45-275
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50-250
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46-50
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40-250
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45-230
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51-55
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35-250
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40-210
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56-60
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35-230
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35-200
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>=61
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30-200
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30-200
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Tanner Stage
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I
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80-250
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80-320
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II
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100-450
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120-450
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III
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250-500
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250-550
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IV
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225-600
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225-600
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V
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225-500
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180-500
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Assay calibrated to WHO 02/254 and instituted at SLCH
5/2018.
Current interpretive criteria established 5-10-2018.
References:
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1. Elecsys IGF-1 Package
Insert 2017-10, V 1.0
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2. Mayo
Medical Laboratories IGFMS entry (https://www.mayomedicallaboratories.com/test-catalog/Overview/62750) accessed 5-9-2018.
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3. Bidlingmaier M, Fredrich N Emen RT et al. J Clin Endocrinol Metab
2014;99:1712-1721
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Critical Values:
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None established
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Limitations:
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Sample should not be taken from patients
receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8
hours following the last biotin administration.
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Methodology:
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Sandwich
principle
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Lab Processing instructions:
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Centrifuge specimen to separate. If specimen is collected in plain, red-top tube aliquot sample into a conical tube for testing (labeling aliquot tube as 'serum').
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Processed Volume:
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0.5 mL (minimum 0.3 mL) serum
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Analyte Stability:
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Ambient - unprocessed: 8 hours
PROCESSED
Ambient: 24 hours
Refrigerated: 48 hours
Frozen: 28 days
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Notes:
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Will also accept Lavender-top (EDTA) plasma; making sure aliquot is labeled as "EDTA plasma"
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EPIC order name:
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Insulin Like Growth Factor (EPIC Test# LAB526)
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Cerner order name:
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IGF1
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CPT Codes:
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84305
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LOINC Value:
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In process
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Synonyms:
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Stomatomedin C; IGF1
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Last Updated: 05/22
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Last Reviewed:
06/23
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