NEWBORN SCREEN, BLOOD SPOT

test app

TEST NAME: NEWBORN SCREEN

The Missouri State Public Health Laboratory (MSPHL) performs laboratory screening for mandated genetic / metabolic conditions on all infants born in Missouri so that early detection and intervention promotes healthy outcomes for those infants with these conditions. It is a state law that each infant born in the state of Missouri is screened for metabolic and genetic disorders.

The Newborn Screening Laboratory currently screens for the following:

Biotinidase Deficiency (BIOT)

Classic Galactosemia (GALT)

Congenital Adrenal Hyperplasia (CAH)

Primary Congenital Hypothyroidism (CH)

Cystic Fibrosis (CF)

Severe Combined Immunodeficiency (SCID)

Spinal Muscular Atrophy (SMA)

Amino Acid Disorders

Fatty Acid Oxidation Disorders

Organic Acid Disorders

Hemoglobinopathies

Lysosomal Storage Disorders

LAB DEPT: Core Lab Sendouts

SPECIMEN REQUIREMENTS

Specimen Type:	Blood Spot
Container/Tube
Preferred/Acceptable:	Newborn Screen filter card
Collection Volume:	5 Defined rings in collection area of card must be completely full of blood by a single application/drop of blood per ring.
Patient Preparation:	Warm infant's heel for at least 1-2 minutes to increase blood flow
Sample Rejection:	Mislabeled or unlabeled specimens. All specimens received at the newborn screening laboratory are examined for specimen acceptability. When the newborn screening laboratory determines a specimen to be poor quality, a same-day fax report is sent to the collecting facility and physician of record requesting a repeat newborn screen immediately
Special Instructions:	Follow "Blood Collection Form Instructions" on back of filter card. Allow blood spots to thoroughly air dry. Blood collection tubes and capillary tubes with EDTA, Citrate or Heparin additives must NOT be used to aid in collection. If infant was born in Illinois and needs screening test, you will need to collect using Illinois Newborn Screening form.

LOGISTICS

Test Availability:	Daily
Turnaround Time:
Lab Testing Section:	Send-outs
Referred to:	Missouri State Public Health Laboratory

INTERPRETIVE

Reference Range:	Normal
Critical Values:	Not established Results that require immediate attention such as high risk results, are phoned and faxed to both the hospital and the physician by the Missouri State Public Health Laboratory. The Missouri State Public Health Laboratory contacts a newborn screening follow up center immediately for appropriate follow up testing, consultation, diagnosis, and treatment.
Limitations:	NA

ADDITIONAL INFORMATION

For SLCH Laboratory use only

Lab Processing instructions:	Allow blood spot to thoroughly air dry for 3-4 hours in a horizontal position, away from direct heat and sunlight. Do not allow the blood to touch any surface during the drying, including other parts of the card. Once dry, cover the blood spots with overlay of card.
Processed Volume:	Blood collection form with all five circles completely filled by single application per circle.
Transport Temperature:	Ambient
Analyte Stability:	NA; however forms should be sent to SPHL within 24 hours of collection
Notes:	To contact the Newborn Screening Laboratory if needed, call 573-751-2662

GENERAL INFORMATION

EPIC order name:	Newborn Screen MO (EPIC Test# LAB480) (or Newborn Screen IL (LAB5769) if born in IL)
Cerner order name:	Newborn Screen Missouri
CPT Codes:
LOINC Value:
Synonyms:
Last Updated: 01/24
Last Reviewed: 01/24