ALPHA-1-ANTITRYPSIN, FECES
test app
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Specimen Type:
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Stool, Random collection |
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Container/Tube
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Preferred:
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Clean, plastic screw capped stool collection container (no preservative) supplied by St. Louis Children's Hospital.
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Acceptable:
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Any clean, plastic screw capped container (no preservative)
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Collection Volume:
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5.0 g (minimum 1.0 mL homogenized stool)
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Patient Preparation:
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None
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Sample Rejection:
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Specimen collected in any preservative or fixative.
Mislabeled or unlabeled specimens.
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Special Instructions:
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None
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Test Availability:
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Daily
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Turnaround Time:
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2-4 days
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Test set-up:
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Monday-Friday
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Lab Testing Section:
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Send-outs
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Referred to:
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Mayo Medical Laboratories (MMLI) / Test ID: A1AF
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Reference Range:
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< or = 54 mg/dL
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Critical Values:
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Not established
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Limitations:
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The clearance studies using 24-hour stool specimens and serum determinations are preferred as it normalizes the large range of serum alpha-1-antitrypsin (A1A) concentrations and the variability in random stool A1A concentration. In the absence of either a 24-hour stool collection or a contemporary serum specimen, the fecal concentration of A1A can be used as a surrogate marker.
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Methodology:
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Nephelometry
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Test Classification:
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This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
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Lab Processing instructions:
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Send entire specimen collection.
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Processed Volume:
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5.0 grams (minimum 1.0 mL homogenized) stool
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Transport Temperature:
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Frozen
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Analyte Stability:
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Ambient: 14 days
Refrigerated: 14 days
Frozen; 14 days
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Notes:
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Random specimen is only acceptable collection type for this orderable. If 24-hour specimen is collected, a serum specimen is also required and test should be ordered as "Misc Ref SLC" in cerner. See Mayo test ID 'CA1A'.
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EPIC order name:
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Alpha 1 Antitrypsin, Stool (EPIC Test# LAB558)
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Cerner order name:
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A1A Feces Rnd
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CPT Codes:
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82103
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LOINC Value:
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9407-8
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Synonyms:
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Last Updated: 01/22
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Last Reviewed: 12/23
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